This review summarizes scientific findings from three European Commission FP7 projects. The first, ARTREAT (2008-2013), focused on a multi-level, patient-specific model of artery and atherogenesis for outcome prediction, treatment decision support, and virtual hands-on training. An original method for plaque formation and development was created an...

By Nenad Filipović, Miloš Radović, Tijana Đukić, Igor Saveljić, Bogdan Milićević, Exarchos Themis, Oberdan Parodi, Dimitris Fotiadis

Aortic dissection is a severe clinical condition that demands a thorough understanding of the interactions between the true and false lumens. In this study, numerical simulations were performed for two patients, generating two preoperative and two postoperative models. The analyses were carried out using the PAKSF solver, a specialized tool for flu...

By Igor Saveljić, Tijana Đukić, Smiljana Tomašević, Nenad Filipović

In silico clinical trials are set to transform medicine by enabling virtual testing and simulation, which streamline the development of medical devices and pharmaceuticals while reducing costs and duration. The SILICOFCM platform offers a innovative, multi-modular approach designed to optimize overall heart function and monitor the effectiveness of...

By Nenad Filipović, Igor Saveljić, Tijana Geroski, Smiljana Tomašević, Miljan Milošević, Bogdan Milićević, Momčilo Prodanović, Srboljub Mijailović, Miloš Kojić

Nowadays, finite element analysis is a well-assessed technique which enables investigation of blood vessels behavior under different boundary conditions. Given the rapid progression of both medical imaging techniques and computational methods, the challenge of using the simulation of human arteries such as carotid arteries to address different medi...

By Smiljana Djorovic, Igor Saveljic, Nenad Filipovic