COMPUTATIONAL MODELING OF DRUG TRANSPORT AND PERFUSION WITHIN COMPLEX BIOLOGICAL SYSTEMS AND GROWING TUMORS
Mass transport is a fundamental process in living organisms, responsible for the delivery of oxygen, nutrients, and drugs from blood vessels to tissues, as well as the removal of waste products back to the vascular and lymphatic systems. This exchange occurs across various biological barriers, including blood vessel walls and cellular membranes, an...
By Vladimir Simić, Miljan Milošević, Bodan Milićević, E.J. Koay, Xuewu Liu, Antonio Martino, Rossana Terracciano, Carly Filgueira, Miloš Kojić
ARTIFICIAL INTELLIGENCE AND MACHINE LEARNING IN HEALTHCARE: ADVANCES AND IMPLEMENTATION CHALLENGES
...
By Igor Saveljić, Miloš Kostić, Slavica Mačužić Saveljić, Žarko Milošević, Nenad Filipović
FAULT DETECTION USING RADIOSENSOR DIAGNOSTICS
...
By Konstantin Boikov
SMEARED CONCEPT FOR MODELING GRADIENT-DRIVEN PROBLEMS IN COMPOSITE MEDIA (KOJIC TRANSPORT MODEL, KTM) AS A BASIS FOR BROAD APPLICATIONS
The extremely complex biological and biochemical processes are mainly treated by laboratory and clinical investigations. In recent decades, the application of computational modeling has become more important in research and applications in the medical sciences. Despite enormous efforts and achievements in this modeling, there is still a need for ne...
By Miloš Kojić, Miljan Milošević, Vladimir Simić, Bogdan Milićević
UNSTEADY MHD NON-NEWTONIAN CASSON FLUID FLOW IN A POROUS MEDIUM WITH CONVECTIVE DIFFUSION, RADIATION, JOULE AND VISCOUS HEATING DISSIPATION EFFECTS: A NUMERICAL STUDY
...
By Bijjula Prabhakar Reddy, Oluwole Daniel Makinde, Paul Majani Matao
CONSTITUTIVE MODELS FOR SOIL AND ROCK
The paper presents the procedure of implicit stress integration for constitutive models for soil and rock. The theoretical basis of Mohr-Coulomb, Matsuoka-Nakai, Hoek-Brown and Hyperbolic soil constitutive models are presented. Stress integration was performed using the theory of incremental plasticity. The general procedure of implicit stress inte...
By Dragan Rakić, Miroslav Živković
PENALTY CONTACT BETWEEN FEM AND SPH WITH FRICTION
The interaction between the Finite Element Method (FEM) and Smoothed Particle Hydrodynamics (SPH) is crucial in multiphysics simulations of granular–structure systems, impacts, and material behavior. This paper presents a penalty-based contact algorithm with Coulomb friction for FEM–SPH coupling. The method accounts for static and dynam...
By Marko Topalović, Miloš Ivanović, Snežana Vulović, Aleksandar Nikolić, Miroslav Živković
OVERVIEW OF SURROGATE MODELING FOR HUXLEY-TYPE MUSCLE SIMULATIONS IN CARDIAC BIOMECHANICS
Huxley-type muscle models offer a physiologically grounded description of cardiac contraction but remain computationally prohibitive for large-scale, multi-scale simulations. This article reviews surrogate modeling strategies that alleviate these costs for ventricular biomechanics, with emphasis on data-driven (RNN/TCN/GRU) and physics-informed (PI...
By Bogdan Milićević, Miloš Ivanović, Boban Stojanović, Miljan Milošević, Miloš Kojić, Nenad Filipović
SOLVING WAVE ACOUSTIC EQUATION USING FINITE ELEMENT METHOD IN PAK SOLVER
Wave acoustic equation is implemented and solved using finite element method in PAK solver to simulate propagation of sound waves, that cause oscillations of ear’s components, such as cochlea (part of inner ear). To simulate mechanical behaviour of cochlea, behaviour of fluid in chambers and behaviour of basilar membrane which separates them ...
By Milica Nikolić, Velibor Isailović, Nenad Filipović
APPLICATION OF PAK SOFTWARE FOR THE CALCULATION OF vFFR IN CORONARY ARTERIES
X-ray angiography is one of the diagnostic procedures applied in clinical practice to analyze the state of patient-specific coronary arteries. During this examination a parameter called fractional flow reserve (FFR) is invasively measured to quantitatively assess the existence of potential stenosis and its significance. The software proposed in thi...
By Tijana Đukić, Ognjen Pavić, Lazar Dašić, Tijana Geroski, Nenad Filipović